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Why Spravato? 

Esketamine's History:

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Esketamine, the active ingredient in Spravato, was first synthesized in the 1960s as a derivative of ketamine, a well-known anesthetic. While ketamine was initially used primarily as an anesthetic, researchers later discovered its antidepressant properties.  

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Key milestones in the history of esketamine:

  • 1962: Esketamine was first synthesized.  

  • 1970s: Ketamine (a racemic mixture of esketamine and arketamine) gained widespread use as an anesthetic.

  • 1997: Esketamine was approved for medical use as an anesthetic in Germany.

  • 2000s: Research began exploring esketamine's potential as a rapid-acting antidepressant.

  • 2019: The FDA approved Spravato® (esketamine) for the treatment of treatment-resistant depression.  

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Esketamine's history highlights its versatility as a medication with both anesthetic and antidepressant properties. Its approval for the treatment of depression represents a significant breakthrough in mental health care, offering a new option for individuals struggling with treatment-resistant depression.  

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Spravato® (esketamine) is a nasal spray prescribed adults dealing with treatment depression (TRD). This treatment can help those who haven't found relief with other medications. Here are some important points to know about Spravato: 

- Spravato® (esketamine) works differently from traditional antidepressants.  Spravato® (esketamine) works by targeting a different receptor in the brain, which can provide rapid relief from depressive symptoms. If you've tried other antidepressants without success, Spravato® (esketamine) may be an option for you. However, it's important to complete a comprehensive assessment, as Spravato® (esketamine) is a controlled substance and requires medical supervision.

Spravato® (esketamine) can provide relief from depressive symptoms within hours of the first dose, offering hope for those struggling with treatment-resistant depression.


- Spravato® (esketamine) has been shown to provide rapid relief. Many users may start to feel better within hours of their first dose. 
- Spravato® (esketamine) is usually prescribed alongside an oral antidepressant for better results. 
- Spravato® (esketamine) can only be obtained through a certified healthcare provider's office or clinic. 

If you're facing challenges with TRD, lets see if Spravato may be right for you. 

“The richest and fullest lives attempt to achieve an inner balance between three realms: love, work, and play.” ~ Erik Erikson

Is it right for you? 

If you've been struggling with depression and traditional treatments haven't provided the relief you need, you're not alone. Treatment-resistant depression occurs when symptoms persist or return despite trying multiple antidepressants and psychotherapy.  It's important to note that Spravato is not a first-line treatment for depression and should only be considered after other options have been exhausted.

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Good Enough is not Good Enough, you can live a full authentic life and you deserve to live a full authentic life

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While treatment-resistant depression can be challenging, there are additional options available:

  • Combination therapy: Combining different antidepressants or adding other medications.

  • Augmentation therapy: Using additional medications to enhance the effectiveness of antidepressants.

  • Ketamine: A newer treatment option that has shown promise for some individuals.

  • Electroconvulsive therapy (ECT): A medical procedure that involves inducing seizures with electrical stimulation.

  • Transcranial magnetic stimulation (TMS): A non-invasive procedure that uses magnetic fields to stimulate areas of the brain.

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Getting Started with Spravato

 

If you're considering Spravato as a treatment option for your treatment-resistant depression, here are the general steps involved:

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  1. Schedule an appointment.  Discuss your symptoms, treatment history, and the possibility of using Spravato.

  2. 90 minute Initial Evaluation: We will assess your suitability for Spravato® (esketamine), including medical history, current medications, and potential risks.  You must complete the portal history and consent to treat 24 hours before the appointment, or we will reschedule. 

  3. If you are appropriate for Spravato® (esketamine) we will write a prescription.  A Certified Pharmacy will manage this. 

  4. Spravato® (esketamine) is only available through certified healthcare providers. Behavioral Health Resiliency PLLC is a Certified REMS Site

  5. You will need to complete the document to be enrolled in the Spravato® (esketamine) REMS Program 

  6. Once you're enrolled in the Spravato REMS program and we have received the approval from your insurance, you'll be able to obtain the medication and undergo the necessary monitoring and support.  

  7. The specific enrollment process may vary depending on your insurance.

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It's important to note that the exact process may vary depending on your individual circumstances. 

If you have any questions or concerns about starting Spravato, schedule an appointment 

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